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Pyrolurea a root cause of depression, anxiety?

Pyroluria is a genetic condition that affects the body’s ability to process and use zinc and vitamin B6. Individuals with this condition produce excessive amounts of a byproduct called kryptopyrrole, which binds to and depletes zinc and vitamin B6. This can lead to a range of physical and psychological symptoms, including ADD, ADHD, depression, anxiety, bipolar disorder, and even schizophrenia.

Pyroluria is the root cause of these conditions because zinc and vitamin B6 are essential for the proper functioning of the nervous system. Zinc is critical for neurotransmitter synthesis and regulation, while vitamin B6 is necessary for the production of serotonin and dopamine, which are two neurotransmitters that play a crucial role in mood regulation. When the body is deficient in these nutrients due to pyroluria, it can lead to a range of mental health issues.

The symptoms of pyroluria can vary, but they often include mood swings, irritability, poor stress tolerance, poor short-term memory, poor dream recall, and poor appetite. These symptoms can be mistaken for other conditions, such as anxiety and depression, which is why pyroluria often goes undiagnosed.

The good news is that pyroluria can be treated through nutritional therapy. Treatment involves supplementing with high doses of zinc and vitamin B6 to restore the body’s levels of these nutrients. This can lead to a significant improvement in symptoms and can even resolve the underlying mental health issues. It is important to work with a healthcare professional to properly diagnose and treat pyroluria to ensure the most effective treatment plan.

Meet the Author

Dr. Matz DC

Dr. Jeffrey E. Matz, DC, MS, is a Board Certified Chiropractic Physician. He is licensed to practice in SC, NC, and GA. Dr. Matz is passionate about functional medicine and strives to help patients achieve optimal health. His focus is on helping our members with hormone imbalances, autoimmune conditions, chronic pain conditions, and diabetes. Among the thousands of people Dr. Matz has treated include Carolina Panthers football players, PGA Tour and Champions Tour golfers, collegiate athletes, and local and international celebrities. Dr. Matz was a semiprofessional cyclist, and has competed in triathlons for the last 7 years, including completing an IRONMAN triathlon.

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