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Low-dose naltrexone (LDN) is a medication that is typically used at a much lower dose than what is typically used to treat addiction or opioid dependence. It is an opioid antagonist, which means that it works by blocking the effects of opioids. It is thought to have a beneficial effect on the immune system and has been investigated for the treatment of a variety of conditions, including autoimmune disorders, cancer, and chronic pain.

The proposed mechanism of action of LDN is that at low doses, it temporarily blocks the action of endorphins, which are natural pain-relieving chemicals in the body. This is thought to trigger an increase in endorphin production, which can help to reduce inflammation and improve the function of the immune system. Studies have suggested that LDN may be useful in treating autoimmune disorders such as multiple sclerosis, Crohn’s disease, and fibromyalgia.

LDN is considered to be safe, with minimal side effects when taken at low doses. Common side effects include sleep disturbances, vivid dreams, and headache. However, it is important to note that the use of LDN is still considered to be experimental, and more research is needed to fully understand its safety and effectiveness. It is important to consult a healthcare professional before starting this medication, specially if you are on other medication or have a medical condition.

Meet the Author

Dr. Matz DC

Dr. Jeffrey E. Matz, DC, MS, is a Board Certified Chiropractic Physician. He is licensed to practice in SC, NC, and GA. Dr. Matz is passionate about functional medicine and strives to help patients achieve optimal health. His focus is on helping our members with hormone imbalances, autoimmune conditions, chronic pain conditions, and diabetes. Among the thousands of people Dr. Matz has treated include Carolina Panthers football players, PGA Tour and Champions Tour golfers, collegiate athletes, and local and international celebrities. Dr. Matz was a semiprofessional cyclist, and has competed in triathlons for the last 7 years, including completing an IRONMAN triathlon.

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