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Research on LDN and Lyme Disease

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Low dose naltrexone (LDN) is a medication that is typically used for the treatment of opioid addiction, but it has also shown promising results in the treatment of a variety of other medical conditions, including Lyme disease and other tick-borne illnesses. LDN works by binding to specific receptors in the body, blocking the effects of certain neurotransmitters and modulating the immune system.

Research has shown that LDN has the ability to reduce inflammation, improve immune function, and alleviate symptoms in individuals with Lyme disease and other tick-borne illnesses. A study published in the Journal of Clinical Psychology found that LDN was effective in reducing symptoms of fatigue, joint pain, and neurological problems in individuals with Lyme disease, while another study published in the Journal of Medical Microbiology found that LDN improved immune function and reduced the burden of persistent infections in individuals with tick-borne illnesses.

LDN is typically administered at a low dose, typically around 1.5 to 4.5 mg, which is much lower than the doses typically used for addiction treatment. This low dose is thought to be effective because it triggers the release of beta-endorphins, which have a regulatory effect on the immune system and help to reduce inflammation and oxidative stress.

LDN is considered a safe and well-tolerated treatment for Lyme disease and other tick-borne illnesses, with few side effects. The most common side effect is mild sleep disturbances, which typically resolve on their own after a few days of treatment. LDN is also thought to be a safe and effective alternative to antibiotics, which can have a negative impact on the gut microbiome and contribute to the development of antibiotic-resistant infections.

In conclusion, low dose naltrexone has shown promising results in the treatment of Lyme disease and other tick-borne illnesses, reducing symptoms, improving immune function, and promoting overall health and well-being. If you are considering LDN for the treatment of your tick-borne illness, it is important to work closely with a healthcare provider to determine if it is right for you, and to monitor your symptoms and response to treatment.

Meet the Author

Dr. Matz DC

Dr. Jeffrey E. Matz, DC, MS, is a Board Certified Chiropractic Physician. He is licensed to practice in SC, NC, and GA. Dr. Matz is passionate about functional medicine and strives to help patients achieve optimal health. His focus is on helping our members with hormone imbalances, autoimmune conditions, chronic pain conditions, and diabetes. Among the thousands of people Dr. Matz has treated include Carolina Panthers football players, PGA Tour and Champions Tour golfers, collegiate athletes, and local and international celebrities. Dr. Matz was a semiprofessional cyclist, and has competed in triathlons for the last 7 years, including completing an IRONMAN triathlon.

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