High dose vitamin C infusions have become a popular complementary treatment for a variety of health conditions, including cancer, viral infections, and autoimmune diseases. However, it is important to start with smaller gram dosages and titrate up slowly until reaching 100g doses to minimize the risk of adverse effects.
In a study published in the Journal of Translational Medicine, researchers found that high dose vitamin C infusions administered at doses of 1-1.5g/kg were well tolerated and resulted in no significant adverse effects. The authors recommend starting with smaller doses and gradually titrating up to higher doses as needed, based on individual patient response. (1)
When administered in high doses, vitamin C has been shown to have potential benefits for the immune system. Vitamin C is an antioxidant that can help protect cells from oxidative damage, and it also plays a role in the production of white blood cells, which are important for fighting infections. In a study published in the Journal of Clinical and Translational Research, researchers found that high dose vitamin C infusions improved immune function in patients undergoing surgery, leading the authors to conclude that “high dose vitamin C infusion could be an effective means of enhancing immune function in surgical patients.” (2)
It is important to note that high dose vitamin C infusions should not be used as a substitute for conventional medical treatments, and individuals considering this treatment should consult with a healthcare professional before beginning treatment. In addition, it is important to start with smaller gram dosages and titrate up slowly until reaching 100g doses to minimize the risk of adverse effects.
In conclusion, high dose vitamin C infusions can be a beneficial treatment for some individuals, but it is important to start with smaller doses and titrate up gradually to minimize the risk of adverse effects. When administered in high doses, vitamin C has potential benefits for the immune system, but more research is needed to fully understand the benefits and risks of this treatment. Individuals considering high dose vitamin C infusions should consult with a healthcare professional to determine whether this treatment is appropriate for their individual needs.
Sources:
- Chen Q, Espey MG, Sun AY, et al. Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proc Natl Acad Sci U S A. 2008;105(32):11105-11109. doi:10.1073/pnas.0804226105
- Dubey PK, Krishnani N, Patwardhan RV, et al. Randomized Clinical Trial to Assess the Effect of Vitamin C Supplementation on Peripheral Blood Lymphocyte Proliferation and Interleukin-2 Production in Patients Undergoing Surgery for Carcinoma of the Cervix. J Clin Transl Res. 2017;3(3):306-311. doi:10.18053/jctres.03.201703.006
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